• What the research says about ingredients used in our cosmetic formulas

    Our formulas combine GHK-Cu Copper Tripeptide-1 with complementary cosmetic ingredients selected for modern skin and hair care.

    Below is a selection of published research relating to ingredients used across the Cu⁺ Hair & Skin range. We focus on cosmetic outcomes such as the appearance of smoother skin, hydration, elasticity and the physical condition of hair.

    Cosmetic Research Overview

    Skin

    • Copper peptides are widely used in topical cosmetic formulations.
    • Research has explored GHK and GHK-Cu for the visible appearance of fine lines, wrinkles, firmness and elasticity.
    • Hyaluronic acid is widely used in skincare for hydration and has been studied in topical cosmetic formulations for skin hydration and elasticity.
    • Cosmetic peptides remain an active area of research, and results from individual ingredient studies should not be assumed to represent the performance of a finished formula.

    Hair

    • Hair care ingredients can influence physical properties such as strength, smoothness and manageability.
    • Panthenol has been studied for its interaction with the hair fibre and its effect on tensile strength.
    • Cosmetic hair products are designed to improve the appearance, feel and condition of the hair.
    • Ingredient research does not establish that a finished cosmetic product will produce the same results.
  • Topical Peptide Treatments with Effective Anti-Aging Results

    Silke Karin Schagen
    Cosmetics (2017)

    Key takeaway: A review of topical peptides used in cosmetic skincare, including copper tripeptide.

    • Reviews the use of peptides in topical cosmetic skincare.
    • Includes copper tripeptide among established cosmetic peptides.
    • Discusses cosmetic research relating to the visible signs of skin ageing.
    • Reviews outcomes including the appearance of wrinkles and skin condition.
    • Highlights that the quality and amount of evidence varies between individual cosmetic peptides.
    See article 
  • Strengthening Benefits of Panthenol for Hair: Mechanistic Evidence from Advanced Spectroscopic Techniques

    Jennifer M. Marsh et al.
    International Journal of Cosmetic Science (2026)

    Key takeaway: Panthenol was shown to interact with the hair fibre and improve measured hair strength.

    • Panthenol was shown to penetrate into the hair fibre.
    • Researchers identified interactions between panthenol and hair proteins.
    • Panthenol-treated hair demonstrated higher break stress than untreated hair.
    • Panthenol-treated hair also demonstrated increased elastic modulus.
    • The findings support the use of panthenol as a cosmetic hair-conditioning ingredient where hair strength is a desired property.
    See article 
  • Topically Applied GHK as an Anti-Wrinkle Peptide: Advantages, Problems and Prospective

    Seyedeh Maryam Mortazavi, Seyyed Ali Mohammadi Vadoud, Hamid Reza Moghimi
    BioImpacts (2025)

    Key takeaway: This review examines GHK and GHK-Cu specifically in the context of topical anti-wrinkle cosmetic formulations.

    • GHK is discussed as a peptide used in topical cosmetic skincare.
    • GHK-Cu is used in cosmetic products formulated for the appearance of ageing skin.
    • The review examines its potential relevance to the appearance of fine lines and wrinkles.
    • Skin permeability and formulation are identified as important considerations for topical peptides.
    See article 
  • Efficacy of Cream-Based Novel Formulations of Hyaluronic Acid of Different Molecular Weights in Anti-Wrinkle Treatment

    Tatjana Pavicic et al.
    Journal of Drugs in Dermatology (2011)

    Key takeaway: Topical hyaluronic acid formulations were studied for cosmetic skin hydration and elasticity.

    • The study evaluated topical hyaluronic acid formulations of different molecular weights.
    • Topical application was associated with improved skin hydration.
    • Improvements in measured skin elasticity were also reported.
    • The research supports the established use of hyaluronic acid in topical cosmetic skincare.
    • Hyaluronic acid is included in selected Cu⁺ Hair & Skin formulas as a hydration-focused cosmetic ingredient.
    See article 

Disclaimer: The research studies, articles, and scientific information presented on this website are provided for educational and informational purposes only. The studies referenced relate to the ingredient GHK-Cu (Copper Peptide) along with other ingredients and not to any specific finished cosmetic product sold by our company. Our products are cosmetic products only and are not intended to diagnose, treat, cure, or prevent any disease, medical condition, or hair loss condition. Any information provided is not medical advice. Always consult a qualified healthcare professional for medical concerns.